The MIIS Eprints ArchiveProtein evolutionPHjorthauthorAmong the proteins that have evolved over hundreds of millions of years, with important roles in defence against invading micro-organisms, are the pentraxins. The two major members of the family are known as CRP and SAP, and they evolve due to mutations in the underlying DNA. The Study Group was asked to construct a model of this evolution in order to answer specific questions about the occurrences of these proteins in man and in the horseshoe crab.Medical and pharmaceutical2001-04Study Group Report

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